Our Research
We are passionate about merging technology with medicine and expediting discovery at the cutting edge of genomic immunology.
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Human T cells drive protection from infection, are central actors in cancer immunotherapy, and drive much of the pathology associated with autoimmune disease. Functional genetic studies in human T cells could reveal pathways that control cell function, prioritize targets for drug development, and improve the design of genetically reprogrammed cell-based therapies.
By developing and applying platforms for CRISPR-Cas9 manipulation and screening in primary human T cells, we explore protein-coding and non-coding genetic mechanisms that regulate T cell functions and work toward therapeutic engineering of cells to treat cancer, HIV, primary immune deficiencies, and autoimmune diseases.
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Support Marson Lab
Our research is made possible by a combination of grants and philanthropic gifts. If you are excited about the work we are doing and are interested in contributing, please get in touch.
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Our People
The Marson lab is a team of highly collaborative students, research technicians, and postdoctoral scientists with expertise across the fields of genomics, immunology, infectious diseases and genome engineering.